ID-5184 Wonca Abstracts supplement A-K 13-10-23 - Flipbook - Page 326
WONCA 2023 Supplement 1: WONCA 2023 abstracts (A–K)
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The risk of all-cause mortality in sarcopenia, sarcopenic
obesity and obesity in ageing: A community-based study
in 2009–21
Dr Hsiang Han Kao1,2,3, Chen Chieh Lin1,4,5, A/Prof Chih Hsueh Lin1,2,4,5, Tsai Chung Li6,7
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Department of Family Medicine, China Medical University Hospital, Taichung, 2Department of Geriatric
Medicine, China Medical University Hospital, Taichung, 3Department of Family Medicine, College
of Medicine, China Medical University, Taichung, 4School of Medicine, College of Medicine, China
Medical University, No. 100, Sec. 1, Jingmao Rd, Beitun Dist, Taichung, 5Department of Medical
Research, China Medical University Hospital, Taichung, 6Department of Public Health, College of
Public Health, China Medical University, Taichung, 7Department of Healthcare Administration, College
of Medical and Health Science, Asia University, Taichung
Introduction
The evidence of the risk of all-cause mortality in sarcopenia and obese ageing people were
controversial. Previous studies suggest low muscle mass was associated with higher mortality.
However, ‘obesity paradox’ has been found in ageing people, which suggest obesity decrease the risk
of mortality.
Objectives
We aim to investigate the risk of mortality in ageing people with sarcopenic obesity (SO), sarcopenia
only (S) and obesity only (O).
Methods
We collected participants above 65 years old in 2009 and followed up until 2021, and mortality data
was recorded. Initially, body composition was measured by dual-energy X-ray. Grip strength and
walking speed were also examined. Sarcopenia was defined according to Asian Working Group for
Sarcopenia in 2019. Obesity was defined as body fat percentage (BF) >25% in males and >30%
in females. The combination of both indicate SO. Cox regression was used for statistical analyses,
adjusting for age, sex, physical activity, alcohol consumption, smoking and baseline disease.
Results
Among 865 participants, the percentages of SO, S and O were 6.8%, 2.4% and 62.7%, respectively.
In the SO group, the average BF was 28 ± 6.17% in males and 36.16 ± 5.46% in females; for
muscle mass, it was 6.36 ± 0.53 kg/m2 in males and 5.12 ± 0.47 kg/m2 in females. Compared with
participants without sarcopenia or obesity, the SO and S groups had significantly increased mortality
(P < 0.01). The O group had significantly decreased mortality compared with the S and SO groups
(P < 0.001). The hazard ratio of all-cause mortality with S and O are 2.02 (95% CI: 1.12, 3.64; P < 0.05)
and 0.69 (95% CI: 0.52, 0.91; P < 0.05), respectively.
Conclusion
Sarcopenia increased the risk of all-cause mortality, while obesity decreased the risk. Besides, there is
no significant effect of sarcopenic obesity on all-cause mortality in our study.
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