ID-5184 Wonca Abstracts supplement A-K 13-10-23 - Flipbook - Page 118
WONCA 2023 Supplement 1: WONCA 2023 abstracts (A–K)
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Prevalence of vitamin D deficiency in hypertensive patients
visiting family medicine clinics in Aga Khan University
Hospital for health check-up
Dr Aayesha Butt, Swaleha Tariq, Mahpara Sadaqat
Aga Khan University Hospital
Introduction
There is a widespread prevalence of (50–90%) of vitamin D deficiency in Pakistan. The National Health
Survey of Pakistan estimated that hypertension affects 18% of adults and 33% of adults below and
above the age of 45 respectively. Literature identifies an inverse relation of vitamin D with plasma renin
activity resulting in hypertension. We assessed the association of vitamin D levels in patients with
hypertension in an outpatient setting.
Objectives
1. To estimate the frequency of vitamin D deficiency in adult patients with hypertension.
2.
To compare the proportion of vitamin D-sufficient or -deficient groups in patients with
hypertension and its associated factors.
Methods
A cross-sectional study enrolled 203 participants with primary hypertension from family medicine
clinics at the Aga Khan University Hospital. Data including demographics, vitamin D levels and factors
associated with hypertension and vitamin D deficiency were noted and analysed using SPSS 20. Post
stratification Chi-squared test was applied taking P ≤ 0.05 as significant.
Results
Of 203 participants, 166 (81.8%) were significantly vitamin D deficient, of which 49.3% were males.
Their mean (±SD) age was 58.2 ± 11.2 years. A significant difference (P < 0.05) in vitamin D levels
among patients with controlled (39.41%) and uncontrolled blood pressures (42.36%) in a hypertensive
population already on antihypertensives was seen. After stratification, a significant difference of vitamin
D deficiency in relation to physical activity (57.1%), salt restriction (33.5%), tobacco smoking (36.4%),
positive sun light exposure (36%) and obesity (57.6%) was also noted.
Conclusion
Pakistan has a heavy burden of hypertension along with high rates of vitamin D deficiency. Our study
found a weak association between vitamin D deficiency and uncontrolled hypertension. To develop
strong association of vitamin D deficiency and hypertension, more studies are required that have
greater data and multiple controlled confounding factors.
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