Final Newsletter 2024 (5) - Flipbook - Page 8
Emerging New Talent
Dr Jamie Burgess
On the 17th of July Jamie graduated from the University of Liverpool
with a PhD, funded by the Pain Relief Foundation, in Obesity and
Endocrinology (Med) where his work focused on the
pathophysiology and diagnosis of neuropathies, with an emphasis
on the contribution of small nerve fibres.
During his PhD, he demonstrated that intra-epidermal nerve fibres
can be processed using an automated immunohistochemistry
staining platform, which he hopes may mitigate downstream
barriers to take-up this diagnostic technique.
He has also implemented other techniques such as corneal
confocal microscopy for quantifying and detecting small fibre
pathology in participants with fibromyalgia syndrome, idiopathic, diabetic, and chemotherapyinduced peripheral neuropathy.
Furthermore, he was able to perform quantitative sensory testing and study symptomatology
as part of deep phenotyping studies in these conditions. His research also included the use of
a large dataset to identify brain alterations as identified by magnetic resonance imaging in
diabetes mellitus and found that these may predate overt end-organ damage. To better
understand the role corneal confocal microscopy may have to improve in the diagnosis of
neuropathies, he has undertaken a Cochrane Diagnostic Test Accuracy Systematic Review to
determine the utility of corneal confocal microscopy in the diagnosis of diabetic
sensorimotor polyneuropathy which he anticipates will inform clinical practice and future
studies
Dr. Jamie Burgess has since had an impressive series of publications, which have made
significant contributions to the field of pain management and relief.
Automated immunohistochemistry of intra-epidermal nerve fibres in skin biopsies: A proofof-concept study Journal of the Peripheral Nervous System - Wiley Online Library
Idiopathic Distal Sensory Polyneuropathy and Fibromyalgia Syndrome: A Comparative
Phenotyping Study: Pain & Therapy(springer.com)
