Immuquest Dx Brochure - Flipbook - Page 8
8
ImmuQuest Ltd - Dx Catalogue
Leukemia/Lymphoma
Antibodies
Leukaemias and lymphomas are cancers arising from cells of the immune
system. Whilst leukaemias are characterised by the presence of malignant
cells in the blood and bone marrow, lymphomas tend to be solid tumours,
often arising in lymph nodes. The diagnosis of leukaemia is usually undertaken
using a process known as immunophenotyping, where analysis of the cell
surface proteins expressed by the tumour cells can be used to identify the
original lineage of the cells. As an example, acute leukaemias may be of the
lymphoid or myeloid lineage, the identification of which with markers such
as CD10 or CD33 guide treatment choices and indeed provide an indication of
long-term prognosis. Flow cytometry is the critical application for Immuquest
antibodies for leukaemia and lymphoma diagnosis, whilst applications such
as immunofluorescence and immunohistology staining are also commonly
used.
Target Antigen
Species Reactivity Tested Applications Clone
SKU
CD8
Human
WB, ICC/IF, Flow Cyt Bu88
IQ672
CD23
Human
ICC/IF, Flow Cyt,
IHC(P)
Bu38
IQ673
CD33
Human
WB, IHC-(Fr), Flow
Cyt, ICC/IF
WM53
IQ473
HLA-ABC
Human
ICC/IF, Flow Cyt
Bu8
IQ681
HLA DP DQ DR
Human
ICC/IF, Flow Cyt
Bu26
IQ682
Parathyroid
Hormone
Human
IHC(P), RIA, ELISA
BAM1916
IQ398
Parathyroid
Hormone
Human
ELISA, IHC(P), RIA
BAM87
IQ399
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