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Advancing innovation and excellence
£274,000
on research and
innovation, including:
£173,000
towards paediatric liver research
£16,000
to purchase a liver digital slide scanner
£17, 500
towards neonatal research
Providing equipment to help
take care further
Last year, thanks to the generosity of our supporters,
we contributed over £16,000 to help the liver
histopathology laboratory purchase a digital slide
scanner that captures a digital image of biopsy tissues
on glass slides. The scanner provides a permanent and
accurate record of the patient’s sample and ensures
urgent pathology can be assessed quickly, remotely
and out of hours – greatly reducing turnaround times.
A donation of £20,000 is being used to fund the
purchase of vital research equipment, test slides and
consumables. The DRI-chemistry analyser – a machine
that can perform multiple test parameters of clinical
chemistry – has been a great tool in providing valuable
data regarding the enzymatic function of liver tissue. The
team hopes to use the remaining funds to purchase test
kits and panels to enable them to conduct single-cell
RNAs sequence experiments. Their findings will provide
advanced information about how to make liver grafts
last longer, as well as help expand the donor pool.
We are continuing our support for a project to improve
treatment for mitral regurgitation, one of the most
common heart valve problems that leads to open heart
surgical repair. Our grant of £10,000 is supporting
Dr Apu Bharucha, a structural heart intervention
research fellow, and his team develop research using
a bench-top heart simulator. In collaboration with
scientists in Canada, they aim to create a life-size
model of a patient’s mitral valve and cavity using 3D
printing techniques. This has huge potential in terms
of research, training and surgery preparation as the
accurate and unique model will help surgeons plan
procedures, as well as practice surgical techniques.
“Such a platform has the potential to help better
identify patients who would benefit from valve
intervention, test novel valve technologies and offer
patient-specific training to surgeons,” says Apu. “One
particular benefit even at this early stage is that it can
help to avoid the need for invasive surgery. For frail
patients, the risks of invasive surgery can outweigh the
benefits, but equipment like this can help achieve great
results without the need for open heart surgical repair."
Projects at King’s can take several years to
implement, depending on their complexity.
This report combines information about grants
committed during 2021/22 with information about
projects that completed during 2021/22, where the
grant was made in previous years.
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