ALT EXAMPLE - MANUAL CREATOR - ALLERGY TESTING - Flipbook - Page 13
Allergy: The Diagnostic Pathway
Symptoms suggestive of
IgE-mediated allergy:
• Eye, nose, chest symptoms
• Eczema
• Urticaria, angioedema, anaphylaxis
NO
YES
Search for sensitization:
• Specic IgE
• Airborne allergens
• Food allergens
NEGATIVE
Is IgE-mediated immediate
hypersensitivity considered
highly likely?
POSITIVE
IgE allergy conrmed
Allergen-specic IgE may
give low positives which have
little clinical meaning—clinical
interpretation is essential
NO
YES
Consider other
mechanisms of disease
Clinical
Immunology/Allergy
Specialist referral
