Catalyst Portfolio Paperturn 3.17.25 - Catalog - Page 1 - Catalog - Page 35
NEW PRODUCT
COSPHADERM® TOCOPHARIN – ANTIOXIDATIVE
PROTECTION FOR SKIN AND FORMULATION
The human skin is a natural protective shield that
is subject to considerable strain over the course
of a lifetime. External influences such as UV radiation, air pollution, stress and cigarette or alcohol
consumption cause additional oxidative stress
and thus contribute to the skin‘s ageing process.
The quality of cosmetic formulations also suffers
from oxidation processes: the oils they contain
become rancid. However, these processes can be
significantly inhibited by choosing suitable antioxidants. Cosphaderm® Tocopharin is an antioxidant blend that combines the protection of the oil
phase of the formulation with a positive influence
on oxidation processes in the skin.
of the formulation. Carnosic Acid obtained from
rosemary (Rosmarinus Officinalis) not only supports the tocopherols in protecting the oil phase,
but also has a distinct effect in protecting the skin
from oxidative stress.
SKIN PROTECTION AGAINST UV
DAMAGE THANKS TO NATURAL
CARNOSIC ACID
Antioxidants play a crucial role in cosmetic products
as they protect the skin from oxidation-induced
damage and associated signs of ageing. As natural plant constituents, antioxidants neutralise free
radicals. With the help of their radical-scavenging
or electron donor properties, they render them
harmless Oxidation processes are mainly caused
by reactive oxygen species (ROS). According to
Loussouarn et al. (2017), the antioxidant effect of
Carnosic Acid is based on chemical quenching of
these reactive oxygen species1.
Consisting of the natural antioxidants Tocopherol
and Carnosic Acid dissolved in Sunflower Oil,
Cosphaderm® Tocopharin as a blend is easy to
use and does not affect the smell or colour of
the formulation. The included mixed tocopherols
contain a high proportion of γ-Tocopherol and
thus ensure excellent protection of the oil phase
100%
ROS levels
80%
60%
92%
93%
74%
20%
100%
40%
UVA
0.003%
BHT
0.003%
Mixed
tocopherols
0.003%
Cosphaderm®
Tocopharin
0%
Figure 1: Fluorometrically determined relative ROS quantity in human keratinocytes after 24-hour incubation with the test substances and subsequent
two-hour UVA irradiation. Samples: untreated UVA-irradiated control (violet), BHT (red), mixed tocopherols (green), Cosphaderm® Tocopharin (blue).
Statistical significance is indicated by * for p < 0.05.
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