الإنتاج البحثي لأعضاء هيئة التدريس بالكلية V.8 - Flipbook - Page 191
ﻣﮭﺎ ﻋﺒﺪ اﻟﻮاﺣﺪ ﺳﻼﻣﻲ.د
أﺳﺘﺎذ ﻣﺴﺎﻋﺪ ﺑﻘﺴﻢ اﻟﺘﺮﺑﯿﺔ اﻟﺒﺪﻧﯿﺔ – ﻛﻠﯿﺔ اﻟﺘﺮﺑﯿﺔ – ﺟﺎﻣﻌﺔ ﻗﻄﺮ
msellami@qu.edu.qa
ORCID
https://orcid.org/0000-0003-1832-409X
Scopus ID
56021097100
(1) Sellami, M., Puce, L., & Bragazzi, N. L. (2023). Immunological Response to Exercise in
Athletes with Disabilities: A Narrative Review of the Literature. Healthcare (Switzerland), 11(12).
https://doi.org/10.3390/healthcare11121692
For a person with a disability, participating in sports activities and/or competitions can be a
challenge for the immune system. The relationship between exercise and immunity response in
disabled athletes is, indeed, extremely complex for several reasons, including (1) the chronic lowgrade inflammatory and immunodepression—“secondary immune deficiency”—state imposed by
the disability/impairment; (2) the impact of the disability on an array of variables, spanning from
physical fitness to well-being, quality of life, sleep, and nutritional aspects, among others, which
are known to mediate/modulate the effects of exercise on human health; (3) the variability of the
parameters related to the exercise/physical activity (modality, frequency, intensity, duration,
training versus competition, etc.); and (4) the intra- and inter-individual variability of the
immunological response to exercise. In able-bodied athletes, previously published data described
several exercise-induced changes affecting various immunological subsets and subpopulations,
ranging from neutrophils to lymphocytes, and monocytes. Broadly, moderate intensity workout is
accompanied by optimal immunity and resistance to infections such as upper respiratory tract
infections (URTI) in athletes. Periods of intense training with insufficient recovery can cause a
temporary state of immunosuppression, which should end with a few days of rest/recovery from
exercise. Disabled athletes are relatively overlooked and understudied with respect to their ablebodied counterparts. Findings from the few studies available on paralympic and disabled athletes
are here summarized and analyzed utilizing a narrative approach to review and determine the major
features of the immunological and inflammatory responses to exercise in this specific population.
Moreover, a few studies have reported behavioral, dietary, and training strategies that can be
adopted to limit exercise-induced immunosuppression and reduce the risk of infection in people
with disabilities. However, given the paucity of data and contrasting findings, future high-quality
investigations on paralympic and disabled athletes are urgently needed
(2) Sellami, M., Elrayess, M., Puce, L., & Bragazzi, N. L. (2022). Molecular Big Data in Sports
Sciences: State-of-Art and Future Prospects of OMICS-Based Sports Sciences. Frontiers in
Molecular Biosciences, 8, 815410. https://doi.org/10.3389/fmolb.2021.815410
Together with environment and experience (that is to say, diet and training), the biological and
genetic make-up of an athlete plays a major role in exercise physiology. Sports genomics has
shown, indeed, that some DNA single nucleotide polymorphisms (SNPs) can be associated with
athlete performance and level (such as elite/world-class athletic status), having an impact on
physical activity behavior, endurance, strength, power, speed, flexibility, energetic expenditure,
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